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Has CGT shown "efficacy"? https://t.co/wf3TZAv4tS -not if you think a study needs double-blinding, patient+therapist not just rater blind, and blind placebo as would the FDA to approve a medical treatment of a subjective psychiatric disorder like grief. https://t.co/GwwzyYyjaI
Bui and Shear coauthor “..CLINICAL INTERVIEW FOR COMPLICATED GRIEF…” https://t.co/hbPds7lVil Bui: says though the CG diagnosis is yet to be validated, “The SCI-CG can be used as validated instrument…” Ergo, we can validate an instrument even when diagnosis is not validated?
Bui: Complicated grief treatment (CGT) has “shown efficacy…across 3...trials” authored by Shear https://t.co/wf3TZAv4tS. Bui has worked with Shear, Director of the “Center for Complicated Grief”, which charge fees for workshops up to $600, https://t.co/h6XFgIwROp
Dr. Bui continues, "...studies have found no...differences between bereavement-related depressive syndromes and non-bereavement related depressive syndromes…The bereavement exclusion was dropped in DSM-5 …”: https://t.co/0ao28lbPRt What's going on here?
Dr. Bui: “Persistent Complex Bereavement Disorder PCBD, ” “has been shown to be distinct from mood, anxiety, and other trauma-related disorders despite.. overlap”. But, “…risk factors for PCBD are similar to those for other bereavement-related conditions: https://t.co/0ao28lbPRt
This move will also spur on use of other indications and targets in adults. I may also show add important information to adverse effect profiles. Us: https://t.co/8JFYE38tUu
The chart doesn't speak to the interaction of diseases-i.e., obesity and diabetes, or smoking and drinking w/mortality. Note, psychiatric conditions aren't on the graph, though they have strong correlations with the big killers. Morbidity is a crucial factor leading to morality.
Sudden Onset of Tics, Tantrums, Hyperactivity, and Lability: https://t.co/9GQYRHXzxk Excellent reminder to think of PANDAS when faced with these kinds of children, usually treated with amoxacillin and naproxen, & led by a pediatric neurologist. Us: https://t.co/sooQBqR2nb
Narcissists should feel rage when unpraised- Likely, the modest praise gave satisfaction-blush, and inflated praise gave proud feeling. The study's problems: subjects' age, validity of personality tests, unblinded nature of researchers, lack of placebo. https://t.co/59gLBhYuMX
NYT “Tell it about You Mother” suggests psychoanalysis caused brain changes https://t.co/pgQ8YqXBv3. There is 1 fMRI image of 1 patient, no results nor analysis & the 1-patient data is a personal contact from the authors to the NYT. NYT should rewrite. https://t.co/We7OmvxoYF
There is indeed more acceptance of mental illness AT work, but not more acceptance of seeing a history of mental illness on an application FOR work. All else being equal, management will likely choose the person without problems. How to change this is the question.
The Army Study to Assess Risk and Resilience in Service members found 1/2 of soldiers had some mental disorder at enlistment: https://t.co/R6m6bs75NU It is challenging to mitigate morbidity as many persons enter the military with mental health problems. https://t.co/59gLBhYuMX
Medications previously tested in other indications may help treat CNS disorders: https://t.co/757bnbaLNx Even anti-cancer drugs are being looked at to treat schizophrenia. This is a great "economy of scale" use of clinical trials. Us: https://t.co/4EE55E1tzZ
Brexanolone is a GABAergic drug for post-partum depression that elevates allopreganolone: https://t.co/ALaXT3h6qb Antidepressants still need to be used in patients however & there is no head-to-head comparison of brexanolone vs. antidepressants yet. Us: https://t.co/6oRuH4YcOU
Effects of acupuncture are the same whether placed along the meridians or at random locations: https://t.co/4kGiSkQBsY Acupuncture studies can not be double-blinded, researchers know which patients receive real acupuncture, likely biasing the results. https://t.co/OIlRSavw02